The UK Biobank Pharma Project publishes early results from its groundbreaking protein research

Olink Proteomics AB

Olink Proteomics AB

UPPSALA, Sweden, June 21, 2022 (GLOBE NEWSWIRE) – Olink Holding AB (yr of publication) (Nasdaq: OLK) has introduced {that a} publication describing early outcomes of protein analysis performed by the UK’s Important Pharma Proteins Venture (UKB-PPP) has been Publish it on-line to bioRxiv Prepress server, obtainable over right here.

The examine is entitledGenetic regulation of human plasma protein in 54,306 UK Biobank membersOlink® Discover 1536 and genome sequencing on 54,306 UK Biobank members to gather and analyze knowledge from protein quantitative trait (pQTL) sitemaps for 1,463 proteins figuring out 10,248 main genetic associations, 85% of which haven’t been beforehand reported.

The outcomes of the UKB-PPP publication present an up to date genetic atlas of plasma proteins and supply the scientific group with an open-access protein supply of broad scope and unprecedented depth to assist elucidate the organic mechanisms underlying genetic discoveries. Measuring hundreds of proteins at a inhabitants scale guarantees to enhance our understanding of the mechanisms underlying illness, thus accelerating the event of latest biomarkers and therapeutics. Moreover, the examine highlights the strengths of Olink’s Discover assay for pQTL and downstream biodetection, with a excessive proportion, 82% of the proteins examined, after Commonwealth of Unbiased States Associations, proof for extremely particular Olink assays that measure supposed proteins.

“The landmark analysis by UKB-PPP members is a significant early step in harnessing the facility of next-generation proteins mixed with genetic info to enhance human well being,” John Hymer, CEO of Olink. “We’re very grateful that Olink’s Discover platform might be part of this large journey, and we eagerly await the total dataset that might be launched to the scientific group by the tip of this yr.”

The UK Biobank Pharma Venture is a collaboration between Biobank within the UK and 13 biopharmaceutical corporations, and is presently conducting one of many world’s largest scientific research of blood protein biomarkers. The UK Biobank is an in depth biomedical database and analysis useful resource containing in-depth genetic and well being info from half one million UK members. The database is globally accessible to researchers and authorized scientists who conduct important analysis in the most typical and life-threatening ailments. The UKB-PPP goals to allow a greater understanding of illness biology and help the event of modern medication for simpler remedies.

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About Olink
Olink Holding AB (Nasdaq: OLK) is an organization devoted to accelerating proteins together with the scientific group, throughout a number of illness areas to allow new discoveries and enhance sufferers’ lives. Olink supplies a platform of services and products deployed throughout main biopharmaceutical corporations and main medical and educational establishments to deepen understanding of human biology in actual time and advance well being care within the twenty first century by means of highly effective and impactful science. The corporate was based in 2016 and is effectively established throughout Europe, North America and Asia. Ulink is headquartered in Uppsala, Sweden. Be taught extra about Olink over right here.

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